| 摘要: |
| 目的:对国内外已发表的关于输尿管软镜软镜联合中药排石汤治疗泌尿系结石的疗效进行Meta分析。方法:计算机检索维普网(VIP)、万方数据知识服务平台、中国知网(CNKI)、中国生物医学文献数据库(CBM)、PubMed英文数据库，检索时间限定为建库至今发表的关于输尿管软镜联合中药排石汤治疗泌尿系结石的临床随机对照试验(RCT)和病例对照研究。由2名评价员按照纳入与排除标准独立筛选文献、提取资料和评价纳入研究质量，采用RevMan 5.3软件进行Meta分析。结果:最终纳入11篇RCT研究，4篇病例对照研究。共1270例患者。Meta分析结果显示:与对照组相比，输尿管软镜联合中药排石汤能提高总体结石清除率[OR=4.32，95%CI(2.97，6.29)，P<0.001]，缩短术后结石排出时间[MD=-3.76，95% CI(-4.75，-2.77)，P<0.001]，减少术后肾绞痛发生[OR=0.28，95% CI(0.13，0.50)，P<0.001]及术后4周结石残留[OR=0.18，95%CI(0.09，0.34)，P<0.001]。结论:采用输尿管软镜联合中药排石汤治疗泌尿系结石能有效提高术后结石清除率，缩短结石排出体外时间，减少术后肾绞痛发生及结石残留。 |
| 关键词: 输尿管软镜 排石汤 临床疗效 Meta分析 |
| DOI：10.3969/j.issn.1007-6948.2022.03.019 |
| 投稿时间：2021-10-16 |
| 基金项目:成都市医学科研课题项目(2021284) |
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| Meta-Analysis of Clinical Efficacy of Flexible Ureteroscopy Combined with Paishi Decoction in Treatment of Urinary Calculi |
| TANG Hao-tong,MAO Min,LIANG Chen |
| Urological Surgical Department,The First People' s Hospital of Shuangliu District, Chengdu 610200, China. |
| Abstract: |
| Objective A meta-analysis was conducted on the efficacy of flexible ureteroscope combined with Paishi decoction in the treatment of urinary calculi published at home and abroad. Methods Computer search for VIP, Wanfang Data Knowledge Service Platform, CNKI, CBM, PubMed English database. The retrieval time was limited to the clinical randomized controlled trials (RCTS) and case-control studies on the treatment of urinary calculi with flexible ureteroscopy combined with Paishi Decoction published so far. Results 11 RCTS and 4 case-control studies were included. There were 1270 patients. The results of meta-analysis showed that compared with the control group, flexible ureteroscopy combined with Paishi decoction could improve the overall calculus clearance rate [OR=4.32, 95%CI (2.97, 6.29), P<0.001], shorten postoperative calculus removal time [MD=-3.76, 95%CI (-4.75, -2.77), P<0.001] as well as reduce postoperative renal colic [OR=0.28, 95%CI (0.13, 0.50), P=0.0008] and residual stone 4 weeks after surgery [OR=0.18, 95%CI (0.09, 0.34), P<0.001]. Conclusion The treatment of urinary calculi with flexible ureteroscopy combined with Paishi decoction can effectively improve the postoperative calculus clearance rate, shorten the time of calculi expulsion from the body as well as reduce the occurrence of renal colic and residual calculi. |
| Key words: Flexible ureteroscopy paishi decoction clinical efficacy Meta-analysis |
