| 摘要: |
| 目的:探讨橡皮生肌膏联合表皮细胞生长因子治疗老年深度烧伤创面的临床治疗效果。方法:将 217例老年深度烧伤患者，随机分为对照组(磺胺嘧啶银乳膏局部包扎换药)、治疗组(橡皮生肌膏 +重组人表皮生长因子凝胶局部包扎换药)。两组病人均使用 1∶10苯扎氯铵盐溶液进行创面消毒，每 2 d换药 1次，至创面愈合。对比两组患者在不同时间点(14 d、21 d、28 d)的创面愈合率，以及创面愈合后的局部瘢痕情况。结果:14 d创面愈合率(%)治疗组(36.6±2.0)比对照组( 20.8±3.8)高。 21 d创面愈合率( %)治疗组( 55.2±2.3)比对照组( 38.3±3.0)高。 28 d创面愈合率( %)治疗组( 75.2±2.4)比对照组( 55.2±3.6)高。治疗组创面愈合时间较对照组存在明显缩短，两者差别具有统计学意义(P＜ 0.05)。治疗组愈合的创面，根据温哥华瘢痕量表(VSS)重度瘢痕数量明显较对照组少。结论:橡皮生肌膏联合应用表皮细胞生长因子在治疗老年深度烧伤中，可以有效的促进患者创面创缘向内爬行，促进创面的愈合与修复，缩短创面愈合时间，并可以减轻后续瘢痕问题对患者的影响。 |
| 关键词: 老年烧伤 深度烧伤 烧伤创面 创面治疗 橡皮生肌膏 |
| DOI：10.3969/j.issn.1007-6948.2021.03.009 |
| 投稿时间：2020-11-19 |
| 基金项目: |
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| Clinical Observation of Rubber Shengji Ointment Combined with Epidermal Growth Factor in the Treatment of Elderly Deep Burn |
| LI Lin,FENG Shi-hai |
| Department of Burn and Plastic Surgery, Af?liated Hospital of Nankai University Fourth Hospital of Tianjin, Tianjin 300222, China |
| Abstract: |
| Objective To investigate the clinical effect of rubber Shengji ointment combined with epidermal growth factor in the treatment of deep burn wounds in the elderly. Methods 217 elderly patients with deep burn were randomly divided into control group (Sulfadiazine Silver Cream local dressing dressing) and treatment group (rubber Shengji ointment plus Recombinant Human Epidermal Growth Factor Gel local dressing dressing). The patients in the two groups were treated with 1:10 benzalkonium chloride solution for local cleaning and disinfection of the wound surface. The frequency of dressing change was once every two days until the wound healed. The wound healing rate at different time points (14 d, 21 d, 28 d) and the local scar after wound healing were compared between the two groups. Results The 14 day wound healing rate (%) in the treatment group was (36.6±2.0) higher than that in the control group (20.8±3.8). The 21 day wound healing rate (%) in the treatment group was (55.2±2.3) higher than that in the control group (38.3±3.0). The 28 day wound healing rate (%) in the treatment group (75.2±2.4) was higher than that in the control group (55.2± 3.6). The wound healing time of the treatment group was signi?cantly shorter than that of the control group (P<0.05). According to the Vancouver Scar Scale (VSS), the number of severe scars in the treatment group was signi?cantly less than that in the control group. Conclusion Rubber Shengji ointment combined with epidermal growth factor in the treatment of elderly patients with deep burn can effectively promote the wound edge crawling inward, promote the wound healing and repair, shorten the wound healing time as well as reduce the impact of subsequent scar problems on patients. |
| Key words: Senile burn deep burn burn wound wound treatment Rubber Shengji Ointment |
