| 摘要: |
| 目的:探讨颅内生殖细胞瘤薄层增强 MR及临床特征，以提高诊断准确性。方法:回顾性分析 51例颅内生殖细胞瘤薄层增强 MR及临床资料。按部位分为 A组(鞍区 +松果体区)17例、B组(侧脑室周围) 22例、C组(基底节 +丘脑区)12例。对三组患者的影像特征及临床资料(包括年龄、性别、形状、生长方式、边界、强化方式、强化程度、椒盐征、伴囊变)进行比较分析。结果:三组的年龄分别为:A组(18.24±4.74)岁， B组(21.68±7.89)岁， C组(19.92±10.61)岁，差异无统计学意义( P=0.395)。性别男 /女比例分别为: A组(9/8)，B组(18/4)，C组(12/0)，P=0.010。形状(团块状 /不规则状)比例分别为:A组(16/1)，B组(22/0)，C组(0/12)，P<0.001。生长方式(肿块型 /蔓延型)比例分别为: A组(17/0)，B组(0/22)，C组(12/0)，P<0.001。边界(清楚 /不清楚)比例分别为: A组(16/1)，B组(20/2)，C组(9/3)， P=0.254。强化方式(均匀 /不均匀)比例分别为: A组(14/3)，B组(9/13)，C组(2/12)，P=0.001。强化程度(轻度 /明显)比例分别为: A组(16/1)，B组(19/3)，C组(11/1)，P=0.708。椒盐征(有 /无)比例分别为: A组(10/7)，B组(13/9)， C组(5/7)，P=0.574。伴囊变(有 /无)比例分别为:A组(7/10)，B组(18/4)，C组(8/4)，P=0.031。三组的性别、形状、生长方式、强化方式、伴囊变比例差异有统计学意义( P<0.05)，三组的边界、强化程度、椒盐征差异无统计学意义 (P>0.05)。结论:颅内生殖细胞瘤患者的性别、病变形状、生长方式、强化方式、伴囊变表现具有部位特征性，患者的年龄、病变边界、强化程度、椒盐征不同部位具有共同性，熟悉颅内生殖细胞瘤的 MR及临床特征，可以提高诊断准确性。 |
| 关键词: 生殖细胞瘤 薄层 增强扫描 MR |
| DOI：10.3969/j.issn.1007-6948.2020.03.030 |
| 投稿时间：2019-07-03 |
| 基金项目: |
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| Thin-layer Enhanced MR Image Analysis of 51 Cases of Intracranial Germinomas |
| BAI Guo-jie,ZHANG Ke-yu,ZHENG Kui-hong |
| Department of Radiology Tianjin Beichen Traditional Chinese Medicine Hospital, Tianjin (300400), China |
| Abstract: |
| Objective The thin-layer enhanced MR findings of intracranial germinomas, which were analyzed to improve the diagnostic accuracy. Methods A retrospective analysis of 51 cases of intracranial germinomas thin-layer enhanced MR imaging data.Divided into parts by group A (saddle region + pineal gland region), group B (around the lateral ventricle), group C (basal ganglia + thalamus region).Statistical analysis of the image characteristics and clinical data of three groups of cases (including age, gender, shape, growth pattern, border, enhancement method, degree of enhancement, pepper and salt sign, and cystic changes). Other data were tested by R * C contingency table chi-square. Results Age, 18.24 ± 4.737 years in group A; 21.68±7.888 years in group B; 19.92 ± 10.613 years in group C, P = 0.395. Gender (male: female), group A (9: 8), group B (18: 4), group C (12: 0), P = 0.010. Shape (mass: irregular), group A (16: 1), group B (22: 0), group C (0:12), P<0.001. Growth pattern (lump type: spread type), group A (17: 0), group B (0:22), group C (12: 0), P<0.001. Boundary (clear: unclear), group A (16: 1), group B (20: 2), group C (9: 3), P = 0.254. Strengthening method (uniform: uneven), group A (14: 3), group B (9:13), group C (2:12), P = 0.001. Degree of enhancement (mild: obvious), group A (16: 1), group B (19: 3), group C (11: 1), P = 0.708. Salt and pepper sign (yes:no), group A (10: 7), group B (13: 9), group C (5:7), P = 0.574. Concomitant cystic changes (yes:no), group A (7:10), group B (18: 4), group C (8: 4), P = 0.031. There were statistically signi?cant differences in gender, shape, growth pattern, strengthening pattern and concomitant cyst changes (P <0.05). There was no statistically significant difference in age, border, degree of strengthening as well as salt and pepper sign (P> 0.05). Conclusion Patients with intracranial germ cell tumor have sex, lesion shape, growth pattern, enhancement pattern and cystic changes. They are characteristics of the patient' s age, lesion boundary, degree of enhancement and different parts of the pepper-salt sign. They are familiar with intracranial germ cell tumors. MR and clinical features can improve diagnostic accuracy. |
| Key words: Germinomas thin-layer enhanced scanning MR |
