| 摘要: |
| 目的:通过荟萃分析( Meta)的方法探讨中医外治治疗糖尿病足的疗效。方法:计算机检索 PubMed、Cochrane Library、Embase、Medline等英文数据库，中国知网法数据库 (CNKI)、维普中文科技期刊全文数据库 (VIP)、万方数据库等中文数据库中关于中医外治法治疗糖尿病足的临床随机对照试验( RCT)，检索时间为建库时间到 2019年 3月 31日，对文献质量进行评价、筛选、提取资料，用 Revman5.3软件进行 Meta分析。结果:本研究共纳入 15篇文献，共 1346名病例，分析结果表明:观察组(中医外治组)治疗有效率明显高于对照组(基础治疗组)，合并 OR(M-H，Fixed，95%CI)为 4.05(2.89,5.67)，漏斗图基本左右对称，发表偏倚较小。结论:在有效率方面，中医外治法优于基础治疗法，但由于缺乏大样本、多中心、设计严谨的临床研究，为临床医师提供循证证据较弱。 |
| 关键词: 中医外治法 糖尿病足 Meta |
| DOI：10.3969/j.issn.1007-6948.2020.01.030 |
| 投稿时间：2019-04-27 |
| 基金项目:国家重点基础研究发展计划( “973”计划)资助项目(2011CB505406) |
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| Therapeutic Effect of External Treatment in Traditional Chinese Medicine on Diabetic Foot: a Meta-analysis |
| TIAN Zhi-kui,ZHUANG Shu-han,GUAN Yuan-yuan |
| Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
| Abstract: |
| Objective To explore the curative effect of external treatment in traditional Chinese medicine (TCM) on diabetic foot by meta-analysis method. Methods Computer retrieval of PUBMED, Cochrane Library, Embase, Medline, Chinese CNKI, Wip database, Wanfang database, etc was performed, the clinical randomized controlled trial (RCT) of TCM external treatment for diabetic foot was searched, the retrieval time was from the time of building the database March 31, 2019. The literature quality was evaluated and screened, the data were extracted, and Revman5.3 software was used for Meta analysis. Results In this study, a total of 1346 cases were included in 15 literatures, and the results showed that the effective rate of treatment was signi.cantly higher in the observation group (TCM external treatment group) than in the control group (basic therapy group), combined with OR (M-H, FIXED, 95%CI) 4.05 (2.89, 5.67), and the funnel diagram was basically symmetrical, the publication is less biased. Conclusion In terms of efficiency, the external treatment method of TCM is superior to the basic therapy method, but the lack of large sample, multi-center and rigorous design of clinical research provides clinicians with weak evidence-based evidence. |
| Key words: Traditional Chinese medicine external treatment method diabetic foot Meta |
