| 摘要: |
| 目的：观察我院自拟方白头翁汤加减治疗大肠湿热型溃疡性结肠炎临床疗效。方法：将 120 例大肠湿热型溃疡性结肠炎患者随机分为治疗组、对照组各 60 例，两组患者均口服美沙拉嗪肠溶片 3 次 /d，2 片 / 次，治疗组给予我院自拟方白头翁汤加减中药汤剂灌肠，对照组给予康复新液 100 mL 保留灌肠，两组均以 10 d 为 1 疗程，期间间隔 2 d 进入下一疗程，共治疗 2 个疗程。结果：治疗组总有效率 90.00%，对照组总有效率 81.67%，治疗组疗效优于对照组（P<0.05），在改善排便次数、便血程度上治疗组优于对照组（P<0.05），而对肠道黏膜修复上两组差异无统计学意义（P>0.05），治疗组较对照组能有效减少治疗复发率（P<0.05）。结论：自拟方白头翁汤加减对大肠湿热型溃疡性结肠炎有较好的治疗效果，值得临床推广。 |
| 关键词: 溃疡性结肠炎 大肠湿热型 白头翁汤 灌肠 |
| DOI：10.3969/j.issn.1007-6948.2019.04.011 |
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| 基金项目:四川省教育厅科研项目（17ZB0123） |
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| Curative Effect Observation of Modified Pulsatilla Decoction in Treatment of Large Intestine Damp-heat Ulcerative Colitis |
| FAN Yong-qiang,ZHANG Rui-fang,CHEN Hong-xia,CHEN Lin,CHEN Chao-hui |
| The First Af?liated Hospital of Chengdu Medical College, Chengdu (610500), China |
| Abstract: |
| Objective To observe the curative effect of modi?ed pulsatilla decoction in treatment of colon syndrome ulcerative colitis. Methods The patients with colon syndrome ulcerative colitis ( 120 cases) were randomly divided into treatment group and control group (n=60), and two groups of patients were orally given Mesalazine Slow Release Tablets (2 tablets each time, 3 times daily). The patients in treatment group were given modi?ed pulsatilla decoction herbal medicinal broth enema, and the patients in control group were given the new recovery liquid (100 mL) for retention enema. Both groups were treated for 10 d as a course, and the interval was 2 d to enter the next course of treatment, with a total of 2 courses. Results The total ef?cacies of treatment and control groups were 90.00% and 81.67%, and the curative effect of treatment group was better than that of control group (P<0.05). The treatment group was superior to the control group in improving defecation frequency and hematochezia degree (P<0.05), but there was no signi?cant difference in intestinal mucosal repair between the two groups (P>0.05). The treatment group could effectively reduce the recurrence rate of treatment compared with the control group (P<0.05). Conclusion The modi?ed pulsatilla decoction has a better therapeutic effect on ulcerative colitis of damp-heat type of large intestine, which is worthy of clinical promotion. |
| Key words: Ulcerative colitis damp-heat type of large intestine pulsatilla decoction enema |
