Efficacy of Hongyu Yuchuang formula combined with negative pressure drainage in patients with postoperative abdominal incisional fat liquefaction
JIA Yan,XU Zhi-yuan,LI Chen-jie
Abstract:
Objective To evaluate the therapeutic effect of Hongyu Yuchuang Formula combined with negative pressure drainage on patients with postoperative incisional fat liquefaction after abdominal surgery by assessing clinical efficacy. Methods A total of 100 patients with postoperative abdominal incisional fat liquefaction admitted to the Affiliated Hospital of North China University of Science and Technology from April 2022 to September 2024 were enrolled in this study. They were randomly divided into a control group (routine dressing change + negative pressure drainage, n=50) and an experimental group (Hongyu Yuchuang formula + negative pressure drainage, n=50). Treatment duration was 14 days. Outcomes included wound recovery (dressing change frequency, hospitalization duration, wound healing time, exudate disappearance time, fresh granulation formation time, wound-skin leveling time), C-reactive protein (CRP), interleukin-6 (IL-6), procalcitonin (PCT), white blood cell count (WBC) levels, and complication rates. Results Compared with the control group, the experimental group had fewer dressing changes (14.28±2.47 vs 21.02±3.61, P <0.05), as well as significantly shorter hospitalization duration, wound healing time, exudate disappearance time, fresh granulation formation time, and wound-skin leveling time (P <0.05). Post-treatment, CRP, IL-6, PCT, and WBC levels were lower in the experimental group (P <0.05). The complication rate was lower in the experimental group (6.00% vs 22.00%, P <0.05). Conclusion Hongyu Yuchuang formula combined with negative pressure drainage significantly improves clinical outcomes in patients with postoperative incisional fat liquefaction. This therapy reduces dressing frequency, shortens hospitalization, accelerates wound healing, alleviates pain, and demonstrates high safety. The mechanism may be related to reducing inflammatory responses and promoting tissue repair.
