Analysis of risk factors for patients undergoing laparoscopic radical resection of colorectal cancer who are transferred to intensive care unit due to complications
LANG Xin-yi,ZHANG Fei-yu,WANG Wen-bo
Abstract:
Objective To explore the risk factors of intensive care unit (ICU) admission due to complications in patients undergoing laparoscopic radical resection of colorectal cancer (CRC) under general anesthesia and to construct a prediction model based on the risk factors. Methods A total of 730 patients who underwent laparoscopic radical resection of CRC under general anesthesia in our hospital from January 2021 to December 2023 were selected. After propensity score matching (PSM), 351 of them were included as the research objects. According to the department transferred to after surgery, they were divided into ICU group (n=117) and general ward group (n=234). Multivariate Logistic regression was used to analyze the risk factors of postoperative complications transferred to ICU. To establish and evaluate a predictive model for admission to ICU due to postoperative complications. Results Multivariate Logistic regression analysis showed that long operation time, large intraoperative blood loss, long recovery time, low degree of differentiation, high TNM stage, intestinal obstruction and preoperative pulmonary complications were risk factors for postoperative complications to ICU. High SpO2, high PaO2/FiO2, restrictive fluid infusion and lung protective ventilation were protective factors for postoperative complications transferred to ICU (P <0.05). A prediction model for postoperative transfer to the ICU due to complications was established: P =1-1/(1+e4.336-0.813×Operation time-0.894×Intraoperative blood loss-0.770×Recovery time+1.321×SpO +1.133×PaO /
