| 摘要: |
| 目的 观察消托清胰汤治疗急性胰腺炎(实热证)的临床疗效和中医证候改善情况。方法:选取2021年8月—2022年10月我院收治的49例急性胰腺炎(实热证)患者，按随机数字表法分为治疗组25例及对照组24例。对照组患者给予禁食水、胃肠减压、生长抑素和奥美拉唑钠等常规治疗。治疗组在对照组基础上服用消托清胰汤。比较两组总有效率、症状缓解时间、中医证候评分、血清酶学指标。结果:治疗组总有效率高于对照组。治疗组腹痛缓解时间、腹胀消失时间、肠鸣音恢复时间、肛门排便时间均明显短于对照组(P＜0.01)。治疗后两组的腹部疼痛、腹部压痛、恶心呕吐、大便不畅评分等较治疗前下降(P＜0.01)；治疗组的腹部压痛、大便不畅评分低于对照组(P＜0.01)。治疗组治疗后口苦口干、胃脘痞闷、嗳气反酸、胸闷气急评分较治疗前下降(P＜0.01)；对照组仅有口苦口干、胸闷气急较治疗前下降(P＜0.05)。治疗组治疗后血淀粉酶及血脂肪酶较治疗前下降(P＜0.01)。结论:消托清胰汤能有效缓解急性胰腺炎(实热证)患者症状、加快胃肠功能恢复、降低血清酶学水平。 |
| 关键词: 急性胰腺炎 消托清胰汤 实热证 临床疗效 中医证候 |
| DOI：10.3969/j.issn.1007-6948.2023.05.004 |
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| 基金项目:大连市中医药医学科学研究计划项目(20Z12003)；第七批全国老中医药专家学术经验继承工作(国中医药办人教函〔2021〕272号) |
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| Observation of efficacy of Xiaotuoqingyi decoction in the treatment of acute pancreatitis |
| ZHAO Liang，GUAN Xi，SHANG Dong |
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| Abstract: |
| Objective To observe the clinical efficacy of Xiaotuoqingyi decoction in the treatment of acute pancreatitis (heat syndrome of the excess type) and the improvement of TCM symptoms. Methods A total of 49 patients with acute pancreatitis were divided into 25 cases in the treatment group and 24 cases in the control group according to the random number table method. The control group was given conventional treatments such as withholding food and water, gastrointestinal decompression, somatostatin and omeprazole sodium. The treatment group added Xiaotuoqingyi decoction on the basis of the control group to compare the total effective rate, symptom relief time, TCM symptom score and serum enzymatic indexes of the two groups. Results The overall effective rate of the treatment group was higher than that of the control group. The time to relieve abdominal pain and disappear abdominal distension, the recovery time of bowel sounds, and the time to defecation in the treatment group were significantly lower than those in the control group (P<0.01). After treatment, the scores of abdominal pain, abdominal tenderness, nausea and vomiting, and poor stool decreased compared with those before treatment (P<0.01), and the scores of abdominal tenderness and unobstructed stool in the treatment group were lower than those in the control group (P<0.01). After treatment, the scores of dry mouth, stomach stuffiness, belching acid reflux and chest tightness and shortness of breath decreased in the treatment group compared with before treatment (P<0.01), while only dry mouth and chest tightness decreased in the control group compared with those before treatment (P<0.05). After treatment, serum enzymatic levels decreased in the treatment group (P<0.01) compared with that before treatment (P<0.01). Conclusion The clinical efficacy of anti-pancreatic decoction in the treatment of acute pancreatitis is definite, and it can effectively relieve symptoms, accelerate the recovery of gastrointestinal function, reduce serum enzymatic level. It is recommended for clinical use. |
| Key words: Acute pancreatitis Xiaotuoqingyi decoction heat syndrome of the excess type clinical efficacy TCM symptom |
