| 摘要: |
| 目的:探讨复方黄柏液联合腔内激光闭合术治疗下肢静脉性溃疡的临床疗效。方法:回顾性分析2020年9月—2021年7月我科收治的58例下肢静脉性溃疡患者，分为三组:腔内激光闭合术+压力治疗归为A组(20例)，复方黄柏液+压力治疗归为B组(19例)，复方黄柏液+腔内激光闭合术+压力治疗归为C组(19例)，收集并分析三组患者术后1个月的临床疗效、预定观察时间的溃疡面积缩小率以及VAS疼痛评分、住院时间等资料。结果:三组患者一般资料比较无统计学意义(P＞0.05)，具有可比性。三组患者1个月内溃疡临床疗效比较差异有统计学意义(P＜0.05)。第1、2、3、4周末，C组溃疡面积缩小率明显高于A、B组，差异有统计学意义(P＜0.05)。C组患者住院时间明显少于A组和B组，差异有统计学意义(P＜0.05)；三组患者治疗前VAS疼痛评分差异无统计学意义(P＞0.05)，具有可比性；第4周末，三组患者VAS疼痛评分差异有统计学意义(P＜0.001)，C组患者VAS疼痛评分明显低于A组和B组，差异有统计学意义(P<0.05)。结论:复方黄柏液联合腔内激光闭合术治疗下肢静脉性溃疡，既能去除病因，又能祛邪扶正、祛腐生肌、抑菌抗炎，可明显缩短溃疡愈合时间，显著改善临床症状。 |
| 关键词: 下肢静脉性溃疡 激光闭合术 复方黄柏液 联合治疗 |
| DOI：10.3969/j.issn.1007-6948.2022.04.005 |
| 投稿时间：2021-11-15 |
| 基金项目:潍坊市科技发展计划项目任务书(2020YX038) |
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| Analysis of Clinical Efficacy of Compound Huangbai Liquid Combined with Intracavitary Laser Closure in Treatment of Venous Ulcers of Lower Extremities |
| CHEN Jun-liang，CHANG Huan-chao，WANG Kai |
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| Abstract: |
| Objective To investigate the clinical efficacy of compound Huangbai liquid combined with intracavitary laser closure in the treatment of venous ulcers of the lower extremities. Methods A retrospective analysis of 58 patients with venous ulcers of the lower extremities in our department from September 2020 to July 2021. Laser closure surgery+pressure therapy were classified as group A, and those treated with compound Huangbai liquid+pressure treatmentalone were classified as group B. Compound Huangbai liquid+Intracavitary laser closure surgery+pressure therapy were classified as group C. The basic data of the three groups of patients were counted, and the clinical efficacy in the three groups of patients within 1 month after the operation, the reduction rate of ulcer area at the scheduled observation time, the VAS pain score and the length of hospital stay were analyzed to evaluate the clinical efficacy. Results There was no statistically significant difference in gender and other general data of the three groups of patients (P>0.05). The clinical efficacy of ulcers in the three groups within 1 month was statistically different (P<0.05). On the weekends of 1, 2, 3 and 4, the reduction rate of ulcer area in group C was significantly higher than that in groups A and B. There was a statistical difference in the reduction rate of ulcer area among the three groups (P<0.05). The length of hospital stay in group C was significantly shorter than that in group A and group B, with statistical difference (P<0.05). The baseline VAS pain score of the three groups was not statistically significant (P>0.05). The VAS pain score of the three groups of patients at the 4th weekend was statistically different (P<0.001). Conclusion Compound Huangbai Liquid combined with intracavitary laser closure in the treatment of venous ulcers of the lower extremities can not only remove the cause, but also dispel pathogens |
| Key words: Venous ulcer of lower extremity laser closure compound Huangbai liquid combination therapy |
