| 摘要: |
| 目的:探讨活血通脉颗粒联合Ilizarov胫骨横向骨搬移术治疗糖尿病足溃疡创面的临床疗效。方法:选取自2017年2月—2020年3月在日照市中医医院骨科住院的58例糖尿病足患者，均采用胫骨横向搬移术治疗，按照治疗方法不同分为中药组与对照组，中药组30例，对照组28例。两组术后常规给予降血糖药物治疗，中药组术后第3天开始口服活血通脉颗粒，对照组术后单纯给予降血糖药物治疗。比较治疗前和治疗后3、6个月两组患者的疼痛视觉模拟(VAS)评分、踝肱指数、患足皮肤温度、10 g尼龙丝检查评分以及患者的溃疡创面愈合时间以评估临床疗效。结果:术后所有患者均获得随访，随访时间6~9个月，平均(7.8±1.3)个月；两组患者治疗3、6个月时的疼痛VAS评分、踝肱指数、患足皮肤温度、10 g尼龙丝检查评分较术前明显改善，差异有统计学意义(P<0.05)；术后3、6个月组间比较，中药组较对照组各项指标改善明显，差异有统计学意义(P<0.05)；中药组溃疡创面愈合时间较对照组明显缩短，差异有统计学意义(P<0.05)。结论:活血通脉颗粒联合胫骨横向骨搬移术治疗糖尿病足临床疗效显著，可有效减轻患足疼痛，改善患肢微循环和皮肤感觉，促进溃疡创面愈合，临床疗效满意。 |
| 关键词: 活血通脉颗粒 胫骨横向骨搬移术 糖尿病足 微循环 |
| DOI：10.3969/j.issn.1007-6948.2021.05.015 |
| 投稿时间：2020-02-18 |
| 基金项目:山东省中医药科技发展计划项目(20190804) |
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| Clinical Observation of Huoxue Tongmai Granules Combined with Tibial Transverse Transport Technique in the Treating Diabetic Foot Ulcers |
| LU Yu-zhou,WU Ya-dong,WU Cheng-qiang |
| Department of Orthopaedics, Rizhao Hospital of Traditional Chinese Medicine, Rizhao, Shandong 276800,China |
| Abstract: |
| Objective To explore the clinical effect of Huoxue Tongmai granules combined with Ilizarov tibial transverse transport technique in the treatment of diabetic foot ulcers. Methods From February 2017 to March 2020, 58 patients with diabetic foot ulcers were treated with tibial transverse transport technique. They were divided into traditional Chinese medicine group and control group according to therapeutic methods. There were 30 patients in traditional Chinese medicine group and 28 patients in control group. They were given hypoglycemic drugs after operation, the patients in traditional Chinese medicine group were given Huoxue Tongmai granules at 3 days after operation. The patients in control group were only given hypoglycemic drugs after operation. The VAS score, ankle-brachial index, the skin temperature of the affected foot, 10g monofilament test score and ulcer wound healing time were all recorded pre and post-operatively to evaluate clinical efficacy. Results All patients were followed for 6 to 9 months (7.8±1.3 months). The VAS score, ankle-brachial index, skin temperature of affected foot and 10g monofilament test score of two groups at 3 months, 6 months after operation were compared with those before operation, which the differences were statistically significant (P<0.05). These indicators in traditional Chinese medicine group at 3 months, 6 months after operation were compared with those of control group, which the differences were statistically significant (P<0.05). The ulcer wound healing time of traditional Chinese medicine group were shorter than that of control group, which the differences were statistically significant (P<0.05). Conclusion The clinical effect of Huoxue Tongmai granules combined with tibial transverse transport technique in the treatment of diabetic foot ulcers patients is signi?cant. Huoxue Tongmai granules can effectively relieve the foot pain, improve the limb microcirculation and skin sensation as well as accelerate ulcer wound healing, which the clinical ef?cacy is satisfactory. |
| Key words: Huoxue Tongmai granules tibial transverse transport technique diabetic foot ulcers microcirculation |
