| 摘要: |
| 目的:探讨骨质疏松性肱骨近端骨折术，给予患者中医活血补骨汤+阿仑膦酸钠治疗对患者术后康复效果产生的影响。方法:选取2019年1月—2020年1月本院收治66例骨质疏松性肱骨近端骨折患者通过随机数字表分作两组。对照组(33例)术后给予阿仑膦酸钠片进行治疗，观察组(33 例)给予阿仑膦酸钠片+活血补骨汤治疗。观察患者治疗后病情恢复时间、疼痛程度、肩关节功能恢复及骨代谢改善情况及并发症发生情况。结果:治疗后与对照组相比，观察肿胀消退、住院天数及骨痂出现、骨折愈合天数均显著更短(t=6.153、5.861、14.163、17.958，均P<0.05)；对比对照组，治疗后1、3、6、12个月观察组NPIS评分均显著更低(t=4.335、10.673、21.542、30.315，均P<0.05)；治疗后观察组肩关节功能恢复优良率为93.94%(31/33)，相比对照组的75.76%(25/33)显著更高，并发症总发生率为3.03%(1/33)，相比对照组的18.18%(6/33)显著更低(χ2 =4.243、3.995，均P<0.05)；治疗后相比对照组，观察组PTH、BALP、β-CTX水平均显著更低，OC则显著更高(t=9.897、3.858、8.942、26.732，均P<0.05)。结论:骨质疏松性肱骨近端骨折患者接受术后治疗后再使用阿仑膦酸钠+活血补骨汤进行辅助治疗，术后恢复速度更快，减轻患者术后疼痛，提高肩关节功能恢复效果，促进患者骨代谢获得良好改善，减少术后并发症，有助于患者术后获得更理想总体康复效果。 |
| 关键词: 骨质疏松 肱骨近端骨折 阿仑膦酸钠 活血补骨汤 骨代谢 肩关节功能 |
| DOI：10.3969/j.issn.1007-6948.2021.04.015 |
| 投稿时间：2020-12-21 |
| 基金项目: |
|
| Effect of Alendronate Combined with Huoxue Bugu Decoction on Shoulder Joint Function and Bone Metabolism in Patients with Osteoporotic Proximal Humerus Fracture After Operation |
| WANG Wan-xiu,YANG Yan-tao,XU Hai-ming |
| Department of Orthopaedics, Wen' an County Hospital of Hebei Province, Hebei 065800, China |
| Abstract: |
| Objective To evaluate the effect of treating osteoporotic proximal humerus fracture with Huoxue Bugu decoction and Alendronate on postoperative rehabilitation. Methods Sixty-six patients with osteoporotic proximal humerus fractures from January 2019 to January 2020 were randomly divided into two groups.The Control Group (33 cases) was treated with Alendronate, and the Observation Group (33 cases) was treated with alendronate and Huoxue Bugu decoction.The recovery time, pain degree, shoulder function, bone metabolism and complications were observed after treatment. Results The time of swelling, hospitalization, Callus and fracture healing in the observation group were shorter than those in the control group(t=6.153, 5.861, 14.163, 17.958, all P<0.05). The NPIS scores of the observation group at 1,3,6 and 12 months after treatment were significantly lower than those of the control group(t=4.335, 10.673, 21.542, 30.315, all P<0.05). The excellent and good rate of shoulder function recovery in the observation group was 93.94% (31/33), which was significantly higher than that in the control group (75.76%)(25/33). The total incidence of complications was 3.03% (1/33), which was significantly lower than that in the control group (18.18%)(6/33)(χ2 =4.243, 3.995, all P<0.05). The levels of PTH, BALP and β-ctx in the observation group were lower than those in the control group, and the OC levels were higher than those in the control group(t=9.897, 3.858, 8.942, 26.732, all P<0.05). Conclusion Patients with osteoporotic proximal humeral fracture were treated with alendronate plus Huoxue Bugu decoction after operation, which can obviously speed up the recovery speed of patients after operation, reduce the postoperative pain, improve the recovery effect of shoulder joint function, improve the bone metabolism of patients and reduce the postoperative complications. It is helpful for patients to obtain more ideal overall rehabilitation effect after operation. |
| Key words: Osteoporosis fracture of proximal humerus alendronate sodium Huoxue Bugu decoction bone metabolism shoulder function |
