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2型糖尿病患者发生小腿肌间静脉血栓的危险因素分析
张明亮,李爱玲,王玉涛
0
济南市中医医院卫生应急办公室济南 250000;滕州市中医医院内分泌科山东枣庄 277599;济南市中医医院周围血管病科济南 250000
摘要:
目的:探讨 2型糖尿病患者发生小腿肌间静脉血栓的危险因素。方法:回顾性分析 2013年 6月—2019年 6月于济南市中医医院内分泌科及滕州市中医医院内分泌科住院治疗的 90例 2型糖尿病患者的临床资料,根据发生小腿肌间静脉血栓与否分为血栓组( n=30)与对照组( n=60),对比分析两组患者的性别、年龄、体质量指数、糖尿病病程等临床资料,进行单因素分析,组间比较有显著差异的单因素,代入二元 Logistic回归分析进行独立危险因素检验。结果:两组患者在年龄、体质量指数、糖尿病病程、合并糖尿病周围神经病变人数、合并活动性溃疡人数、合并冠心病人数、合并高血压人数、吸烟人数、血糖控制方案、白细胞计数、血小板计数、凝血酶原时间、活化部分促凝血酶原激酶时间、纤维蛋白原、 D-二聚体、纤维蛋白原降解产物、红细胞沉降率等方面组间比较差异无统计学意义(P>0.05);在性别、合并糖尿病周围血管病变人数、糖化血红蛋白水平、超敏 C反应蛋白水平差异有统计学意义(P<0.05)。Logistic回归显示,糖化血红蛋白高水平、超敏 C反应蛋白高水平为 2型糖尿病患者发生小腿肌间静脉血栓的独立危险因素。结论:糖化血红蛋白高水平、超敏 C反应蛋白高水平为 2型糖尿病患者发生小腿肌间静脉血栓的独立危险因素。
关键词:  小腿肌间静脉血栓  2型糖尿病  危险因素
DOI:10.3969/j.issn.1007-6948.2021.04.006
投稿时间:2020-12-15
基金项目:山东省中医药科技发展计划( 2019-0559);济南市第二届优秀卫生计生人才培养项目(济卫科外发〔 2018〕号);济南市第三批“薪火传承 231工程”培养项目(济中医药发〔2017〕11号);济南市卫生健康系统青年岗位能手培养项目(济D-卫发〔 2019〕1号);济南市卫生健康委员会科技计划项目( 2019-
Analysis of Risk Factors of Calf Muscular Venous Thrombosis in Patients with Type 2 Diabetes Mellitus
ZHANG Ming-liang,LI Ai-ling,WANG Yu-tao
Emergency Response Office, Jinan Municipal Hospital of Traditional Chinese Medicine, Jinan (250012), China.
Abstract:
Objective To investigate the risk factors of calf muscular venous thrombosis in patients with type 2 diabetes mellitus. Methods The clinical data of 90 patients hospitalized in Jinan Municipal Hospital of Traditional Chinese Medicine and Tengzhou Traditional Chinese Medicine Hospital from June 2013 to June 2019 were retrospectively analyzed. The patients were divided into thrombosis group and control group according to the occurrence of calf muscular venous thrombosis. The clinical data of the two groups, such as age, body mass index, duration of diabetes were compared and analyzed in a single-factor analysis. The single factors with signi?cant differences between two groups were substituted into binary Logistic regression analysis for independent risk factor test. Results There were no statistically significant differences in age, body mass index, duration of diabetes, number of patients with diabetic peripheral neuropathy, number of patients with cardiovascular disease, number of patients with hypertension, number of smokers, methods of glucose control, count of white
Key words:  Calf muscular venous thrombosis  type 2 diabetes mellitus  risk factors

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