| 摘要: |
| 目的:探讨中医辨证分型内服汤剂治疗在肛门直肠神经官能症中的临床疗效，为临床提供新的治疗方法和理论基础。方法:本研究纳入81例肛门直肠神经官能症患者，采用中医辨证分型内服汤剂治疗49例，采用口服氟哌噻吨美利曲辛片32例，根据治疗前后患者症状好转情况、治疗前后焦虑及抑郁评分比较以评价两组患者疗效。结果:两组患者在年龄、性别、BMI、是否抽烟、病程、治疗前焦虑评分、治疗前抑郁评分均无统计学差异(均P＞0.05)，说明两组患者有可比性。随访期间，观察组中患者，痊愈23例，好转19例，无效7例，有效率为86%，治愈率为47%；对照组中患者，痊愈10例，好转16例，无效6例，有效率为81%，治愈率为31%。两组患者有效率对比差异有统计学意义(P=0.038)，两组患者治愈率差异比较无统计学差异(P=0.157)。观察组中患者治疗前后平均焦虑评分(5.96±2.491 vs 3.959±1.527)，平均抑郁评分(11.10±2.284 vs 5.041±2.272)，对照组中患者治疗前后平均焦虑评分(6.66±3.033 vs 4.281±1.650)，平均抑郁评分(10.41±2.138 vs 6.375±2.296)，差异均有统计学意义(均P＜0.05)；治疗后观察组和对照组平均焦虑评分(3.96±1.527 vs 4.28±1.651)差异无统计学意义(P=0.372)，治疗后两组患者平均抑郁评分(5.041±2.272 vs 6.375±2.296)差异有统计学意义(P=0.012)。结论:中医辨证分型内服汤剂及氟哌噻吨美利曲辛片均可用于治疗肛门直肠神经官能症，其中中医辨证分型内服汤剂效果更优于氟哌噻吨美利曲辛片。 |
| 关键词: 肛门直肠神经官能症 中医辨证分型 氟哌噻吨美利曲辛片 |
| DOI：10.3969/j.issn.1007-6948.2021.01.006 |
| 投稿时间：2020-03-11 |
| 基金项目:山东省自然科学基金资助项目(ZR2015 CL029) |
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| Efficacy of Different Diagnositication of Traditional Chinese Medicine in the Treatment of Anorectal Nerve Functional Disorder |
| JIN Zhen-mei,ZHI Chong-yang |
| Department of Anorectal Surgery, Weifang Hospital of Traditional Chinese Medicine, Weifang 261041, China |
| Abstract: |
| Objective To explore the clinical efficacy of different diagnositication of traditional Chinese medicinal decoction in the treatment of anorectal nerve functional disorder and to provide a new treatment method and theoretical basis for the clinic. Methods 81 patients with anorectal nerve functional disorder were enrolled. Among them, 49 patients were treated with different diagnositication of traditional Chinese medicine (medicinal decoction), 32 patients with flupentazol and melitrazine. Anxiety score, depression score before and after therapy and the improvement rate of patients were used to evaluate the therapy. Results There were no significant differences in age, gender, BMI, smoking, disease duration, anxiety score and depression score between the two groups, indicating that the two groups were comparable. The treatment period of the two groups was 1 month, and the follow-up period was 1 year. Among the experimental group, 23 patients were cured , 19 patients were improved , 7 patients were ineffective. The effective rate was 86% and the cured rate were 47%. In the control group, 10 patients were cured, 16 patients were improved and 6 patients were ineffective. The effective rate was 81%, the cured rate was 31%. There was a statistically significant difference in the effectiveness of the two groups of patients (P=0.038), and there was no significant difference in cure rate between the two groups (P=0.157). The anxiety scores were (5.96±2.491 vs 3.959±1.527), while the depression scores were (11.10±2.284 vs 5 . 041 ±2 . 272 ) in observation group before and after therapy. The anxiety scores were ( 6 . 66 ±3 . 033 vs 4 . 281 ±1 . 650 ), while the depression scores were (10.41±2.138 vs 6.375±2.296) in the control group before and after therapy. The results showed significant differences (all P＜ 0.05). After treatment, the anxiety scores among observation group was (3.96 ±1.527), while it was (4.28±1.651) among control group. There were no signi?cant difference (P=0.372). However, the depression scores among observation group was (5.041±2.272), while it was (6.375±2.296) in the control group. There were signi?cant differences (P=0.012). Conclusion The treatment of anorectal nerve functional disorder by different diagnositication of traditional Chinese medicine (herbs decoction) is better than that of |
| Key words: Anorectal nerve functional disorder different diagnositication of traditional Chinese medicine ?upentixol melitrazine |
