| 摘要: |
| 目的:探讨血必净联合连续肾脏替代治疗(CRRT)对外科术后脓毒症患者炎性因子与凝血功能的影响。方法:将2016 年3 月1 日—2018 年12 月1 日本院ICU 科所收治的术后脓毒症患者158 例纳入此次研究，依据治疗方案的不同，分成对照组52 例、血必净组53 例与联合组(血必净+ 血液净化)53 例，比较治疗前与治疗后48 h 三组的血清炎性因子(CRP、LPS、PCT 及IL-10、IL-6、IL-1b)、凝血功能(APTT、PT、FIB)、肾功能(血Scr 与BUN)、氧合指数及APACHE Ⅱ评分。 |
| 关键词: 血必净 连续肾脏替代治疗 脓毒血症 炎性因子 |
| DOI：10.3969/j.issn.1007-6948.2020.02.015 |
| 投稿时间：2019-05-28 |
| 基金项目: |
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| Effect of Xuebijing Combined with CRRT on Inflammatory Factors and Coagulation Function in Patients with Sepsis after Operation |
| WANG Shu-ying |
| Department of ICU2 Surgical ICU, Tianjin Fourth Centre Hospital, Tianjin 300140,China |
| Abstract: |
| Objective To investigate the effect of Xuebijing and CRTT on patients with sepsis after ICU,and its effects on inflammatory factors and coagulation function. Methods A total of 158 patients with postoperative sepsis admitted to the ICU from March 1, 2016 to December 1, 2016 were included in the study.They were divided into the control group by 52 patients and the Xuebijing group by 53 patients and combined group (Xingbijing+blood purification) by 53 patients according to the digital table method. According to the different treatment options, before and after 48h treatment, serum inflammatory factors (CRP, LPS, PCT and IL-10, IL-6, IL-1b), coagulation function (APTT, PT, FIB), renal function (blood Scr and BUN) ,oxygenation index and APACHE Ⅱ score were observed and compared. Results After treatment, the coagulation function related |
| Key words: Xuebijing CRTT sepsis inflammatory factors |
