| 摘要: |
| 目的:系统评价清热活血中药复方治疗慢性前列腺炎的临床疗效和生活质量。方法:通过检索对中国知网、中国医院数字图书馆、中国生物医学文献数据库、 PubMed外文数据库 2000年 1月至今发表的关于清热活血中药复方治疗慢性前列腺炎的临床随机对照试验( RTC)文献，提取资料后采用 Cochrane及 Jadad评分标准对文献进行质量评价，并采用 Review Manager 5.3软件进行数据分析。结果:共纳入 9个 RCT研究，对 822例患者进行 Meta分析。采用清热活血法治疗慢性前列腺炎患者，其中医证候疗效 [RR=1.2，95% CI(1.12，1.29)]；疼痛症状评分 [MD= –2.88，95% CI(–4.13，–1.64)]；排尿症状评分 [MD= –0.93，95% CI(–1.83，–0.03)]；生活质量评分 [MD= –1.75，95% CI(–2.37，–1.13)]均优于对照组。结论:采用清热活血中药复方治疗慢性前列腺炎可减轻患者疼痛症状及排尿症状，提高患者生活质量及中医临床疗效。 |
| 关键词: 清热活血 慢性前列腺炎 临床疗效 生活质量 Meta分析 |
| DOI：10.3969/j.issn.1007-6948.2020.01.031 |
| 投稿时间：2019-04-19 |
| 基金项目:深圳市宝安区医疗卫生科研项目( 2018JD020)；深圳市科技计划项目( JCYJ20180302144752020)，深圳市科技计划项目(JCYJ20160426095604511) |
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| Meta-analysis of Clinical Efficacy and Quality of Life in Treatment of Chronic Prostatitis with Qingre Huoxue Therapy |
| YOU Xu-jun,FU Wei,ZHANG Qing |
| Department of Andrology, Shenzhen Baoan Traditional Chinese Medicine Hospital, Shenzhen (518101), China |
| Abstract: |
| Objective To systematicly evaluate the clinical ef.cacy and quality of life of Qingre Huoxue Recipe in treating chronic prostatitis. Methods A randomized controlled clinical trial of Qingre Huoxue Recipe for the treatment of chronic prostatitis published by China Knowledge Network (CNKI), China Hospital Digital Library (CHKD), China Biomedical Literature Database (CBM), and PubMed Foreign Language Database from January 2000 to present. The test literature, after extracting the data, used Cochrane and Jadad scoring standards to evaluate the quality of the literature, and used Review Manager 5.3 software for data analysis. Results A total of 9 RCT studies were included and Meta-analysis was performed on 822 patients. Analysis showed that the treatment of chronic prostatitis with Qingre Huoxue method, TCM syndrome RR = 1.2, 95% CI (1.12, 1.29); pain symptom score MD = –2.88, 95% CI (–4.13, –1.64); urination Symptom score MD= –0.93, 95% CI (–1.83, –0.03); quality of life score MD= –1.75, 95% CI (–2.37, –1.13). Conclusion Treatment of chronic prostatitis with Qingre Huoxue TCM compound can alleviate pain symptoms and urinary symptoms and improve patients’ quality of life and clinical ef.cacy of TCM, and is superior to the control group. |
| Key words: Qingre Huoxue chronic prostatitis clinical ef.cacy quality of life Meta-analysis |
