| 摘要: |
| 目的：观察当归四逆汤组方在游离皮瓣修复手部组织缺损中的临床疗效。方法：将 60 例手部组织缺损患者随机分为两组各 30 例，对照组在游离皮瓣修复术后常规抗感染、抗凝、抗痉挛治疗；观察组除常规治疗外，结合当归四逆汤口服， 连用 7 d。两组的皮瓣的修复情况通过成活率和优良率两个指标进行比较。计量资料通过完全随机两样本t 检验或进行比较； 计数资料则通过卡方检验或 Fisher 确切概率法进行比较；等级资料通过 Wilcoxon 秩和检验进行比较。结果：观察组优 14 例， 良 9 例，可 7 例，差 0 例，优良率 77%，成活率 100% ；对照组优 8 例，良 7 例，可 14 例，差 1 例，优良率 50%，成活率 97%。就优良率而言，两组差别有统计学差异，且观察组优于对照组（P<0.05）；就成活率而言，两组未见统计学差异（P>0.05）。结论：游离皮瓣修复手部组织缺损术后，应用当归四逆汤可以有效提高皮瓣优良率，获得满意的治疗效果。 |
| 关键词: 当归四逆汤 游离皮瓣 手部组织缺损 |
| DOI：10.3969/j.issn.1007-6948.2019.05.031 |
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| 基金项目:河北省中医药管理局科研计划项目（2017138） |
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| Application of Danggui Sini Decoction in Repair of Hand Tissue Defect with Free Skin Flaps |
| ZHANG Ning,HE Chun-yuan,XIU Xiao-lei |
| Cangzhou Hospital of Integrated TCM-WM, Cangzhou (061001), China |
| Abstract: |
| Objective To observe the clinical curative effect of Danggui Sini Decoction (DSD) on the repair of hand tissue defects in free skin ?ap. Methods Sixty patients with hand tissue defect were randomly divided into two groups, 30 patients in each group, and the patients in control group were treated with traditional anti- in?ammatory, anticoagulant and anticonvulsive therapy after free skin ?ap repair. In addition to the traditional treatment, the patients in observation group were given combination with DSD for 7d after operation. The repair of skin ?aps of two groups was compared by survival rate and superior rate. The measurement data were compared by the t-test of two samples. The counting data were compared by chi-square test or Fisher exact probability method. The rank data were compared by Wilcoxon rank sum test. Results In the observation group, there were excellent 14 cases, good 9 cases, medium 7 cases, and poor 0 case, with superior rate of 77% and survival rate of 100%. In the control group, there were excellent 8 cases, good 7 cases, medium 14 cases and poor 1 case, the superior rate was 50%, and the survival rate was 97%. There were statistically signi?cant differences between the two groups in terms of superior rates, and the observation group was superior to the control group (P=0.032). In terms of survival rate, no statistical difference was found between the two groups (P=0.500). Conclusion In free ?ap in repairing tissue defect postoperative, DSD can effectively enhance the survival rate of ?ap and obtain satisfactory therapeutic effect. |
| Key words: Danggui Sini Decoction free ?ap ?nger |
