| 摘要: |
| 目的：观察宁泌泰胶囊和盐酸特拉唑嗪胶囊联合体外冲击波碎石术（ESWL）治疗输尿管上段结石的疗效。方法： 选择行 EWSL 治疗的湿热蕴结型输尿管上段结石的患者 98 例，按照数字表法随机分为观察组和对照组，各 49 例。观察组口服宁泌泰胶囊和盐酸特拉唑嗪胶囊，对照组口服盐酸特拉唑嗪胶囊。比较两组的排石率、疼痛程度、二次 ESWL 例数等指标。结果：2 周内和 4 周内，观察组排石率分别为 74.5% 和 89.4%，明显优于对照组的 52.1% 和 72.9%（P<0.05）；观察组二次碎石率为 25.5 %，明显低于对照组的 47.9%（P<0.05）；观察组疼痛视觉模拟评分法评分≥ 4 分者占 68.1%，低于对照组的 85.4%（P<0.05）。两组不良反应发生率比较差异无统计学意义（P>0.05）。结论：宁泌泰胶囊和盐酸特拉唑嗪胶囊联合治疗可以明显提高输尿管上段结石 ESWL 的结石排净率，缩短排石时间，减少 ESWL 的次数，减轻患者痛苦。 |
| 关键词: 宁泌泰胶囊 特拉唑嗪 输尿管上段结石 体外冲击波碎石术 |
| DOI：10.3969/j.issn.1007-6948.2019.05.011 |
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| 基金项目: |
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| Effect of Ningmitai and Terazosin Combined with Extracorporeal Shock Wave Lithotripsy for Treatment of Upper Ureter Calculi |
| ZENG Huan-cong,WEN Wei-jun,YAN Chao,HE Jie-fang |
| Department of Urology, Shunde Hospital of Guangzhou University of Traditional Chinese Medicine, Foshan (528300), China |
| Abstract: |
| Objective To observe the clinical effect of Ningmitai Capsule and Terazosin ombined with extracorporeal shock wave lithotripsy (ESWL) in treatment of upper ureteral calculi. Methods Totally 98 patients with upper ureteral calculi with damp-heat accumulation were randomly divided into observation group (n =49) and control group (n =49), and were treated with ESWL. The patients in observation group were given Ningmitai Capsules and Terazosin Capsules, and the patients in control group were given Terazosin Capsules. The rate of stone removal, the degree of pain and the number of second ESWL cases were compared between the two groups. Results The stone removal rates of the observation group were 74.5% and 89.4% within 2 weeks and 4 weeks respectively, which were significantly higher than those of the control group (52.1% and 72.9%) (P<0.05). The secondary lithotripsy rate of the observation group was 25.5%, which was signi?cantly lower than that of the control group (47.9%, P<0.05). The visual analogue score ≥ 4 of the observation group was 68.1%, which was signi?cantly lower than that of the control group (85.4%, P<0.05). There was no statistical difference in the incidence of adverse reactions between the two groups (P >0.05) Conclusion Ningmitai Capsule combined with Terazosin hydrochloride after ESWL can significantly improve the stone removal rate of upper ureteral calculi, shorten the time of stone discharge, reduce the number of ESWL, and alleviate the pain of patients. |
| Key words: Ningmitai Capsule Terazosin upper ureter calculi extracorporeal shock wave lithotripsy |
