| 摘要: |
| 目的：探讨高流量湿化氧疗治疗干燥综合征继发肺间质纤维化的临床临护理措施。方法：回顾性分析我院自 2010年 5 月—2017 年 12 月期间收治的 39 例干燥综合征继发肺间质纤维化患者。其中 2010 年 5 月—2015 年 9 月期间收治的 20例患者给予常规呼吸疾病综合治疗护理设为对照组 20 例。2015 年 10 月—2017 年 12 月期间收治的 19 例患者在常规呼吸疾病综合治疗护理基础上予高流量湿化氧疗护理治疗设为观察组 19 例。回顾性分析两组患者在治疗开始前、开始后 24 h、48 h 呼吸频率、动脉血气分析及痰液黏稠度的改善情况。结果：两组患者年龄、性别、病程等一般情况比较无统计学差异（P>0.05）。两组在治疗开始前呼吸频率、动脉血气分析结果比较差异无统计学意义（P>0.05）；两组在治疗开始后 24 h呼吸频率、pH、PaCO2 无统计学差异（P>0.05），比较 PaO2（86.33±7.23），（90.43±7.56）有统计学差异（P<0.05）。两组在治疗开始后 48 h 呼吸频率比较差异无统计学意义（P>0.05），比较 pH、PaO2、PaCO2 差异有统计学意义（P<0.05）。两组患者组内比较对照组治疗开始前、开始后 24 h、48 h 呼吸频率、pH、PaCO2、PaO2 比较有统计学差异（P<0.05）；观察组治疗开始前、开始后 24 h、48 h 呼吸频率、pH、PaCO2、PaO2 比较有统计学差异（P<0.01）。两组患者在治疗开始前组间比较痰液黏稠度无差异统计学意义（P>0.05），24 h、48 h 后组间比较痰液黏稠度差异有统计学意义（P<0.01）。结论：高流量湿化氧疗结合呼吸道治疗干燥综合征继发肺间质纤维化的患者，疗效肯定，安全可靠，值得推广应用。 |
| 关键词: 高流量 氧疗湿化 干燥综合征 肺间质纤维化 肺功能 |
| DOI：10.3969/j.issn.1007-6948.2019.04.034 |
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| 基金项目: |
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| Nursing Research on Patients with Secondary Pulmonary Fibrosis of Sjogren’s Syndrome with High flow Humidifying Oxygen therapy |
| Qin Lie,Yan Peng-bo,Li Yan-lin,LI Shuang,YUN Xue-jiao |
| Department of Nursing, Tianjin Beichen Hospital, Tianjin (300400), China;Department of Critical Care Medicine, Beichen Hospital, Tianjin (Tianjin 300400) |
| Abstract: |
| Objective To explore the clinical nursing measures of high ?ow humidi?cation oxygen therapy for secondary pulmonary interstitial fibrosis in sclerosing syndrome. Methods Retrospective analysis was performed on 39 patients with secondary pulmonary interstitial ?brosis due to scleroderma syndrome admitted and treated in our hospital from May 2010 to December 2017. Among them, 20 patients admitted and treated from May 2010 to September 2015 were given comprehensive treatment and nursing of conventional respiratory diseases, and 20 patients were set as the control group. From October 2015 to December 2017, 19 patients of observation group were given high-flow humidification oxygen therapy and nursing treatment on the basis of comprehensive treatment and nursing of conventional respiratory diseases. The improvement of respiratory frequency, arterial blood gas analysis and sputum viscosity in the two groups before, 24 h and 48 h after treatment was retrospectively analyzed. Results There were no statistically significant differences between the two groups in age, gender, course of disease and other general conditions (P < 0 . 05 ). There was no statistically signi?cant difference in respiratory frequency and arterial blood gas between the two groups before the treatment (P>0.05). There was no statistically signi?cant difference in respiratory frequency, pH, and PaCO2 between the two groups 24 h after the start of treatment (P>0.05), and there was statistically significant difference in PaO2 [(86.33±7.23) and (90.43±7.56)] (P<0.05). There was no statistically significant difference in respiratory frequency between the two groups 48 h after the start of treatment (P >0.05), and the differences in pH, PaO2 and PaCO2 were statistically signi?cant (P<0.05). The respiratory frequency, pH, PaCO2, and PaO2 between the two groups before, 24 h and 48 h after treatment in the control group were compared, and there were statistically signi?cant differences (P<0.05). The respiratory frequency, pH, PaCO2 and PaO2 of the observation group were compared before, 24 h and 48h after treatment, and there were statistically significant differences (P < 0. 01). There was no statistically significant difference in sputum viscosity between the two groups before treatment (P>0.05), and there was statistically signi?cant difference in sputum viscosity between the two groups after 24 h and 48 h of treatment (P < 0.01). Conclusion The efficacy of high flow humidification oxygen therapy combined with respiratory tract therapy for patients with sclerosing syndrome secondary pulmonary interstitial ?brosis is positive, and it is safe and reliable, worthy of promotion and application. |
| Key words: High flow humidification Sjogren' s syndrome pulmonary interstitial fibrosis lung function |
